Lilith (Blanchett), an infamous bounty hunter with a mysterious past, reluctantly returns to her home, Pandora, the most chaotic planet in the galaxy. Her mission is to find the missing daughter of Atlas (Ramírez), the universe's most powerful S.O.B. Lilith forms an unexpected alliance with a ragtag team of misfits - Roland (Hart), a seasoned mercenary on a mission; Tiny Tina (Greenblatt), a feral preteen demolitionist; Krieg (Munteanu), Tina's musclebound protector; Tannis (Curtis), the oddball scientist who's seen it all; and Claptrap (Black), a wiseass robot. Together, these unlikely heroes must battle an alien species and dangerous bandits to uncover one of Pandora's most explosive secrets. The fate of the universe could be in their hands - but they'll be fighting for something more: each other.

After returning to her home planet Pandora, infamous outlaw Lilith is given a dangerous mission and forms an alliance (and potential friendship) with other criminals, including former mercenary Roland, demolitionist Tiny Tina and her protector Krieg, insane scientist Tannis, and the wisecracking robot Claptrap. The mission: find and protect the missing (and important) daughter of a powerful man named Atlas. But things may not be as they seem, as the girl holds the key to great power that can change the fate of the universe. The popular video game set on the abandoned fictional planet of Pandora where people search for a mysterious relic.